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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
19.39
Human Site:
S97
Identified Species:
30.48
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S97
Q
K
L
S
V
I
S
S
N
T
L
R
G
R
S
Chimpanzee
Pan troglodytes
XP_510301
627
67581
P76
G
A
C
L
Q
S
S
P
P
G
A
S
P
P
T
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S97
Q
K
L
S
V
I
S
S
N
T
L
R
G
R
S
Dog
Lupus familis
XP_544614
968
105825
S384
Q
K
L
S
V
I
S
S
N
T
L
R
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
N98
K
L
S
V
I
S
S
N
T
L
R
G
R
S
P
Rat
Rattus norvegicus
Q62829
544
60692
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
D88
Y
V
S
G
L
L
N
D
L
Q
K
L
S
V
I
Chicken
Gallus gallus
XP_426393
667
74767
S97
Q
K
L
S
A
I
S
S
N
T
L
R
G
R
S
Frog
Xenopus laevis
NP_001082100
650
73749
M92
L
L
D
E
F
D
D
M
S
V
C
R
S
N
S
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
S97
S
R
L
S
V
T
S
S
N
S
L
R
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
T88
N
N
N
K
A
D
T
T
S
L
N
S
S
S
T
Honey Bee
Apis mellifera
XP_001122147
624
70155
K73
P
T
E
I
L
D
L
K
T
I
V
R
G
H
N
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
S21
P
P
I
R
F
S
S
S
A
T
R
E
N
Q
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
A248
V
K
P
S
K
P
E
A
K
S
K
P
V
S
V
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
R246
N
T
D
S
K
A
A
R
S
S
K
P
S
K
S
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
6.6
0
N.A.
0
93.3
13.3
60
N.A.
0
13.3
20
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
26.6
0
N.A.
20
93.3
20
73.3
N.A.
26.6
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
14
7
7
7
7
0
7
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
14
0
0
20
7
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
7
0
0
7
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
0
0
0
0
0
7
0
7
34
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
7
7
7
27
0
0
0
7
0
0
0
0
7
% I
% Lys:
7
34
0
7
14
0
0
7
7
0
20
0
7
7
0
% K
% Leu:
7
14
34
7
14
7
7
0
7
14
34
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
14
7
7
0
0
0
7
7
34
0
7
0
7
7
7
% N
% Pro:
14
7
7
0
0
7
0
7
7
0
0
14
7
7
7
% P
% Gln:
27
0
0
0
7
0
0
0
0
7
0
0
0
7
0
% Q
% Arg:
0
7
0
7
0
0
0
7
0
0
14
47
7
27
0
% R
% Ser:
7
0
14
47
0
20
54
40
20
20
0
14
27
27
47
% S
% Thr:
0
14
0
0
0
7
7
7
14
34
0
0
0
0
14
% T
% Val:
7
7
0
7
27
0
0
0
0
7
7
0
7
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _